Table 1:

Listing of suggested publications to further the understanding of the biochemical and mechanistic aspects.
Year Title Reference
1987 High-resolution crystal structure of cytochrome P450cam [6]
1989 Crystal structure of the carbon monoxide-substrate-cytochrome
P-450cam ternary complex
[7]
1995 Crystal structure of cytochrome P450cam complexed with
its catalytic product, 5-exo-hydroxycamphor
[8]
2002 Regioselectivity of CYP2B6: Homology modeling, molecular
dynamics simulation, docking
[9]
2002 Oxidizing species in the mechanism of cytochrome P450 [10]
2003 Horseradish peroxidase: A valuable tool in biotechnology [11]
2004 Radical rebound mechanism in cytochrome P-450-catalyzed hydroxylation
of the multifaceted radical clocks α-and β-thujone
[12]
2005 Comparative pharmacokinetics of vitamin K antagonists: Warfarin,
phenprocoumon and acenocoumarol
[13]
2007 The Cytochrome P450 Engineering Database: A navigation and prediction
tool for the cytochrome P450 protein family
[14]
2007 A flexible approach to induced fit docking [15]
2008 Cytochrome P450 Structure and Function: An Evolutionary Perspective [16]
2009 Identification of selectivity-determining residues in cytochrome P450
monooxygenases: A systematic analysis of the substrate recognition site 5
[17]
2009 Mechanism of oxygen activation and hydroxylation by the aromatic amino
acid hydroxylases
[18]
2009 Hydrocarbon hydroxylation by cytochrome P450 Enzymes [4]
2010 Prediction and analysis of the modular structure of cytochrome
P450 monooxygenases
[19]
2011 Heme biology: The secret life of heme in regulating diverse
biological processes
[20]
2011 RS-Predictor: A new tool for predicting sites of cytochrome
P450-mediated metabolism applied to CYP 3A4
[2]
2011 Identification of CYP1A2 ligands by structure-based and
ligand-based virtual screening
[21]
2011 Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline
IQ-143 on metabolism and its regulation in Staphylococcus aureus,
Staphylococcus epidermidis
and human cells
[22]
2011 Structure, mechanism and function of cytochrome P450 enzymes [23]
2012 Metallocenes as target specific drugs for cancer treatment [24]
2012 Handbook of porphyrin science [25]
2012 Cytochrome P450 monooxygenases: An update on perspectives
for synthetic application
[26]
2012 Identification of selectivity determinants in CYP monooxygenases
by modelling and systematic analysis of sequence and structure
[27]
2012 Computational prediction of metabolism: Sites, products, SAR, P450
enzyme dynamics, and mechanisms
[28]
2013 Crystal structures and functional characterization of wild-type
CYP101D1 and its active site mutants
[29]
2014 Inhibitory potency of 8-methoxypsoralen on cytochrome P450 2A6 (CYP2A6)
allelic variants CYP2A6*15, CYP2A6*16, CYP2A6*21 and
CYP2A6*22: Differential susceptibility due to different
sequence locations of the mutations
[30]
2014 Conservation analysis of class-specific positions in cytochrome
P450 monooxygenases: Functional and structural relevance
[31]
2015 Electrocatalytic cycle of P450 cytochromes: The protective
and stimulating roles of antioxidants
[32]
2015 Development of a pharmacogenetics-based warfarin dosing algorithm
for Thai patients
[33]